abstract：:The effect of mild heat shock on the replication of human cytomegalovirus (HCMV) was studied in human embryo fibroblasts. Treatment of cell cultures at 44 degrees C for 10 min just before infection or at 24 h post infection (p.i.) shortened HCMV eclipse period and enhanced viral replication, while heat shock performed...

journal_title：Virus research

authors： Zerbini M,Musiani M,La Placa M

更新日期：1986-12-01 00:00:00

abstract：:A cell-free system was developed to study the replication of simian rotavirus SA11. The components of the system included (i) subviral particles prepared from infected cells to template the synthesis of viral RNA and (ii) an mRNA-dependent rabbit reticulocyte lysate to support protein synthesis. Based upon nuclease-se...

journal_title：Virus research

authors： Patton JT

更新日期：1986-12-01 00:00:00

abstract：:The purpose of this study was to test whether the region coding for subgroup envelope specificity was a determinant of oncogenic potential. An avian retrovirus recombinant was constructed to contain the envelope gene (env) determinant for subgroup A of an avian RNA tumor virus in one of the non-oncogenic, endogenous a...

journal_title：Virus research

authors： Wright SE,Bennett DD

更新日期：1986-11-01 00:00:00

abstract：:The capsid structures of the 7 serotypes of foot-and-mouth disease virus have been compared utilizing a series of neutralizing monoclonal antibodies which were previously shown to recognize at least 4 distinct epitopes on type A12 virus. A radioimmune binding assay using radioactively labeled antigens and the monoclon...

journal_title：Virus research

authors： Grubman MJ,Morgan DO

更新日期：1986-10-01 00:00:00

abstract：:African swine fever virus induces in Vero cells 81 acid and 14 basic polypeptides which account for most of the information content of the virus DNA. The kinetics and the cytosine arabinoside sensitivity of the synthesis of the virus-induced polypeptides showed the existence of three classes of proteins, two early and...

journal_title：Virus research

authors： Santarén JF,Viñuela E

更新日期：1986-09-01 00:00:00

abstract：:The human respiratory coronavirus OC43 was grown on a human rectal tumor cell line and was isotopically labeled with amino acids, glucosamine, and orthophosphate to analyze virion structural proteins. Four major protein species were resolved by electrophoresis and many of their properties were deduced from digestion s...

journal_title：Virus research

authors： Hogue BG,Brian DA

更新日期：1986-08-01 00:00:00

abstract：:The pathogenesis of chorioallantoic membrane (CAM) infection with herpes simplex virus 1 and 2 (HSV-1 and HSV-2) as well as chick embryo fibroblast (CEF) passaged HSV-1 was studied. It was found that HSV-2 is at least a million-fold more virulent than HSV-1 as measured by pfu/LD50 ratios for the embryo. Serial passage...

journal_title：Virus research

authors： Goodman JL,Stevens JG

更新日期：1986-08-01 00:00:00

abstract：:This report provides evidence for the replication of varicella zoster virus (VZV) in Raji cells. Infection was achieved by co-cultivation of Raji cells with VZV-infected human fibroblasts. Replication of VZV, as assessed by immunofluorescence using monoclonal antibodies against VZV-glycoproteins, ranged from 18 to 24%...

journal_title：Virus research

authors： Cauda R,Chatterjee S,Tilden AB,Grossi CE,Whitley RJ

更新日期：1986-06-01 00:00:00

abstract：:It has previously been shown that the shortest RNA (RNA 7) of influenza C viruses codes for a nonstructural (NSI) protein (Nakada et al. (1985) J. Virol. 56, 221-226). Experiments reported here indicate that RNA 7 also directs the synthesis of a second nonstructural protein via a spliced mRNA. The amino terminal 62 co...

journal_title：Virus research

authors： Nakada S,Graves PN,Palese P

更新日期：1986-05-01 00:00:00

abstract：:The genomes of eight hepatitis A virus (HAV) strains originating from far distant geographic regions such as Europe, North Africa, Middle and North America, Australia and The People's Republic of China were compared by RNase T1 oligonucleotide mapping. For this purpose, the viruses were propagated in cell cultures and...

journal_title：Virus research

authors： Weitz M,Siegl G

更新日期：1985-12-01 00:00:00

abstract：:The coronavirus JHMV persistently infects rat Schwannoma cells RN2-2 at 32.5 degrees C and enters a host-imposed reversible, latent state at 39.5 degrees C. JHMV can remain up to 20 days in the latent state and about 14 days before the cultures lose the capacity to resume virus production upon return to 32.5 degrees C...

journal_title：Virus research

authors： Coulter-Mackie M,Adler R,Wilson G,Dales S

更新日期：1985-10-01 00:00:00

abstract：:Infected cell protein 10 (ICP10) or antigen 4 (Ag4) and infected cell-specific protein 11/12 (ICSP11/12) have been suggested as specific antigenic markers for cervical carcinoma. Experiments were designed to determine whether ICP10 and ICSP11/12 are distinct antigens and to determine the cellular localization of ICP10...

journal_title：Virus research

authors： Flanders RT,Kucera LS,Raben M,Ricardo MJ Jr

更新日期：1985-04-01 00:00:00

abstract：:Borna disease virus grows to low titres in persistently infected cells with an infectious particle to cell ratio of 0.01 to 0.05. Inclusion of n-butyrate in the growth medium enhances infectivity yields up to 1 log. This effect is time and concentration dependent. In hypertonic medium with an excess of NaCl, KCl or Na...

journal_title：Virus research

authors： Pauli G,Ludwig H

更新日期：1985-02-01 00:00:00

abstract：:Damage to the Kupffer and endothelial cells of the liver sinusoids induced by the administration of sublethal doses of frog virus 3 (FV 3) renders A/J mice which are genetically resistant to mouse hepatitis virus type 3 (MHV 3) highly susceptible to this virus. Liver histopathology of these animals revealed typical ne...

journal_title：Virus research

authors： Pereira CA,Steffan AM,Kirn A

更新日期：1984-10-01 00:00:00

abstract：:The epitopes of six monoclonal antibodies generated against type A12 foot-and-mouth disease virus (FMDV) VP1 or its largest cyanogen bromide fragment (13 kd) were characterized. Five of these monoclonal antibodies neutralized viral infectivity. Solid-phase and competitive antigen binding assays using virion-derived an...

journal_title：Virus research

authors： Robertson BH,Morgan DO,Moore DM

更新日期：1984-09-01 00:00:00

abstract：:The complete nucleotide sequence has been determined for the S RNA of Aino virus, a member of the Simbu serogroup (Bunyavirus genus, family Bunyaviridae). The S RNA is 850 nucleotides long (2.76 X 10(5) daltons) and in the viral complementary sequence has a short 5' non-coding region of 34 nucleotides and a more exten...

journal_title：Virus research

authors： Akashi H,Gay M,Ihara T,Bishop DH

更新日期：1984-01-01 00:00:00

abstract：:Purified retrovirus RD114 p30 was found to bind to the extracellular matrix proteins, fibronectin and laminin. The purified matrix proteins were immobilized onto polystyrene and the binding of p30 was quantitated using radioiodinated proteins and enzyme immunoassay (EIA). The dissociation constants were for the p30-fi...

journal_title：Virus research

authors： Salonen EM,Suni J,Vaheri A

更新日期：1984-01-01 00:00:00

abstract：:Normal mouse lymphocytes were implanted with EBV receptors and exposed to the virus of P3HR-1 strain. 5% of the cells expressed early (EA) and viral capsid (VCA) antigens as assayed by immunofluorescence 24 h after the infection. Only 0.1% of cells expressed nuclear-like antigen (EBNA) 48 h post-infection. When labell...

journal_title：Virus research

authors： Sinangil F,Volsky DJ

更新日期：1984-01-01 00:00:00